2007. Further, fresh onion (Allium cepa) and radish (Raphanus sativus) extract also inhibited the erythrocyte membrane lipid peroxidation effectively in a dose dependent manner. The result of the examination of biochemical parameters of creatinine levels statistic showed significant (p<0.05) decrease in the dose 18 and 36 mL/kg BW compare with the negative group. Cellular responses to oxidative stress: adaptation, damage, repair, senescence and death 5. Radiobiol. Membranes, were probed with anti-SOD-1 (1:500), anti-PRDX-1, (1:1000) and anti-actin (1:2000) purchased from Abcam, (Abcam, Massachussetts, USA). - A noter qu'en cas de troubles hépatiques, la dose conseillée est de 8 g par jour (ce qui n'est pas possible avec des gélules contenant seulement 200 mg). Comprendre l'hépatite A. L'hépatite A est une maladie infectieuse virale du foie qui provoque des lésions inflammatoires réversibles. The new method is aiming to help students as well as lecturers... My area of focus is on the alterations of genetic and epigenetic factors which are contributing to cancer progression and metastasis. Effect of curcumin on, normal and tumor cells: role of glutathione and bcl-2. 1, 1 Nov 2013 | International Immunopharmacology, Vol. Results: All medicaments significantly (p<0.05) showed reduced ALT, AST, ALP, ALB, BIL and increased TP levels, with G. latifolium exhibiting greater efficacy than A. dentate. In the chloroform fraction, curcumin was found to be the main compound, together with xanthorrhizol as a minor compound. Each value represents the mean ± SEM of triplicates for 3 repeated experiments. Treatment with C. longa and CUR also improved immunoglobulin E (Ig)E, pro-inflammatory cytokine interleukin 4 (IL)-4, transforming growth factor-beta, IL-17, interferon-gamma levels, and type 1/type 2 helper cells (Th1)/(Th2) ratio in conditions with disturbance in the immune system. oxygen species (ROS), both in vitro and in vivo. Further, the histopathology analysis of intestine confirmed the better protective effect of CGM over UC-treated animals. IJPPE has an editorial policy of publishing original, high scientific quality and interesting Reviews, Research Articles, Methods, Techniques and Evaluation Reports, Editorials and Short Communications to publish in all areas of Biosciences, Medicine, Medicinal Chemistry and Pharmaceutical Sciences including Natural Product, Pharmacognosy and Phytochemistry Research. treated diabetic rats. High performance liquid. Trouvé à l'intérieur – Page 333The Effectiveness of Fermented Turmeric Powder in in Subjects with Elevated Alanine Transaminase Levels A Randomised Controlled ... Effects of Curcuma Longa ( Turmeric ) on Postprandial Plasma Glucose and Insulin in Healthy Subjects . 2021, 1 Jun 2015 | Phytochemistry Letters, Vol. 1991; Singh et al. A mes amies d'enfance, Agathe et Julie, pour toutes ces années d'amitié et tant de bons moments partagés. Immunostimulatory activities. 13, No. © 2014, Babol University of Medical Sciences. Physiol. Mice were pretreated with DATS (30mg/kgbw) for 7d before being exposed to ethanol (4.8g/kgbw). their formulation. *. Certaines herbes et épices peuvent réellement vous aider à faire baisser votre tension. 10 novembre 2020 - 18 h 27 min. Le curcuma réduit l'inflammation dans tout le corps, améliore les fonctions cardiovasculaires et fait tomber la tension. Determination of a sublethal dose of g-radiation and the protective role of Curcuma longa (CL) extract on rat hepatocytes. Traitement Naturel Hyperferritinémie. 2001; Kang, pande et al. Il existe 2 transaminases dont le coenzyme est la vitamine B6 (phosphate de pyridoxal) : TGO ou ASAT : cette transaminase se trouve […] Cancer chemoprotective effects ofCurcuma xanthorrhiza, Combined Inhibitory Effect of Curcuma Xanthorrhiza Extract and Xylitol on Streptococcus Mutans and Actinomyces Viscosus. 3) +/- des ingr dients non indiqu s. Cas du Fortodol* sens contenir du curcuma longa, mais qui contient aussi du nimesulide (anti-inflammatoire h patotoxique). 1194. doi:10.1016/0006-2952(91)90253-2. An acetone extract of Curcuma xanthorrhiza rhizomes and the nhexane Elles sont présentes dans tous les tissus, mais leur taux dans le sang à une concentration élevée est souvent lié à des maladies du myocarde ou plus souvent du foie. Histopathological and Biochemical study on the effect of flavonoids isolated from the plant Curcuma longa effective in liver enzymes (GOT, GPT) to female rats infected eggs diabetes induced in alloxan. Curcuma is prized because of its long, tubular rhizomes, which have a bright orange color. ... C. longa extract also showed a hepatoprotective effect on morphological changes in the liver of rats induced by γ-irradiation, as evidenced by the occurrence of regular hepatic lobules with normal circular nuclei and a normal central vein. Significant increases in the levels of various cytokines in the plasma were detected before an increase in plasma transaminase levels. Changes occurred in the, tissue levels of trace elements, and the protein levels of SOD-1 and PRD. However, CGM treatment was found to provide better clastogenic and genotoxic potential as compared to UC. chemistry approach to overcoming radiation injury. Reactive species and disease: fact, fiction or filibuster? Appa-, a consequence response to abnormal stress, might be impli-, exhibits deleterious effects on biological macromolecules, such as proteins, lipids, and DNA. Trouvé à l'intérieur – Page 90( Deshpande UR , Joseph L ) , Manjure SS , Bhide SV , Samuel AM ; Effect of turmeric extract on lipid profile ... Curcumin administration resulted in returning alkaline phosphatase and aspartate transaminase activities to near normal ... chemiluminescence substrate (ECL; Pierce, USA). and Mc Farlin et al. All solutions were, prepared with ultra-pure water having a specific resistance, Liver tissues were homogenized in radio-immunoprecipitati, supernatant was collected for measuring the protein concen-, tration using a BCA protein kit (Pierce, USA). Trouvé à l'intérieur – Page 89We assessed hepatic injury (transaminases) and function [bile production and sulfobromophthalein (BSP) clearance, ... Fresh data on Antioxidants are presented in the report “Radioprotective effect of Curcuma longa extract on ... 3, 1 Jan 2009 | Biological & Pharmaceutical Bulletin, Vol. In this paper, the recent development in the study of the epidemiology of hepatocellular carcinoma (HCC) and the diagnosis of adenomatous hyperplastic nodules as a putative preneoplastic lesion are discussed. However, DATS pretreatment dramatically attenuated these adverse effects. Seven metals, including Fe, Cu, Zn, Mn, Ca, and Se, were detected in the plant tissue. Découvrez Germanium - 1 L de Catalyons Laboratoire à 28,95 €. Utilisé comme épice, le curcuma est connu pour aider notre corps à digérer les graisses et stimuler la production de bile. Objective: Turmerin, a protein from Turmeric, the powdered rhizome of the herb Curcuma longa L. (Zingiberaceae) is investigated for its ability to prevent oxidative organ damage against Naja naja venom phospholipase A 2 (NV-PLA 2) in Male Swiss Wistar mice. 2000). IAEA. Catalyons Laboratoire Germanium - 1 L livré en 24/48h, paiement sécurisé sur Onatera. Values for, membranes, lipid peroxidation is reported to be particularly, susceptible to radiation damage (Chevion et al. -irradiation 6.5 Gy, followed by daily admin-, ) (IAEA 1980), sample digestion was carried out using a, /cm, obtained from ELGA. Eurasia J Biosci. 344. doi:10.1016/0300-483X(81)90027-5. The largest area under a curve, -irradiation, followed by treatment for additional, -irradiation caused a significant decrease, extract in modulating the antioxidant en-, ). The increase in serum TGs after ir, resulted either from the inhibition of lipoprotein lipase activ-, ity (Sedláková et al. These findings suggest that CKS may prevent ethanol-induced acute liver injury, possibly through its ability to block CYP2El-mediated ethanol bioactivation and its free radical scavenging effects. 2017; Larrey D. Post'U 2019 2) Souvent achet s sur internet. J. Agric. The results showed that the acetone extract and the nhexane fraction exhibited significant activities against Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus, and weak activities against Shigella dysenteriae and Vibrio cholerae. Anti-IL-6 antibody blocked the IL-1-induced increase in plasma ACTH, whereas recombinant IL-6 by itself did not induce such an increase. The mechanism of temulawak as a hepatoprotector by reducing serum enzyme levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and γ-glutamyl transferase (GGT) [9]. Access scientific knowledge from anywhere. View abstract. Therefore, the handling of this issue should be done seriously, one of them through an exploration of drug discovery and drug material. CURCUMA (estomac et intestin) Extrait titré en curcumine Dyspepsies Troubles de la perméabilité intestinale 1 comprimé 3 fois par jour avant les repas . 12, 19 September 2014 | Helvetica Chimica Acta, Vol. Red lentil extract administration significantly reduced the activity of liver enzymes compared with carbon tetrachloride. Cell, reduced glutathione concentration and the activity of glutathione, reductase in some tissues of the rats gamma-irradiated after the. Le curcuma a aussi un effet protecteur sur les reins, car les produits toxiques, les métaux lourds endommagent aussi les reins au passage. Journal of Babol University of Medical Sciences. Depuis trente ans, de nombreuses recherches scientifiques ont été menées sur le desmodium, justifiant l'utilisation traditionnelle de cette plante, et elles se poursuivent aujourd'hui.Ainsi, il a été démontré, sur des souris, que cette plante supprimait la phase tonique des convulsions, lors des crises d'épilepsie.D'autres études ont mis en lumière les propriétés hépato . Trop de Transaminases et de Gamma GT? C'est la raison pour laquelle le surpoids et l'obésité sont des facteurs de risque importants. Purpose Strenuous exercise induces inflammation and muscle damage. soluble antioxidant peptide from turmeric. Georges Maalouly. The last two decades have observed a major shift towards investigating natural products as radioprotectors, as these are immensely effective in terms of their potential bioequivalence relative to many of the established synthetic compounds available. Please check your inbox for the reset password link that is only valid for 24 hours. *, p < 0.05 compared with the control or irradiated cells. It may be concluded that C. xanthorrhiza can protect the liver from various hepatotoxins, hence C. xanthorrhiza could be useful in the treatment of liver injuries and has promise as a kind of broad spectrum hepatoprotective agent. Roxb. Asian J. Androl. Trouvé à l'intérieurLes hépatites toxiques ou médicamenteuses Atteinte cytolytique (transaminases augmentées) : extrait de desmodium/chardon-Marie/curcuma ou romarin ââ qsp 150 ml. Atteinte cholestatique (PAL, ƔGT augmentées) : extrait ... The results revealed that oral administration of kefir significantly reduced the radiation-induced hepatic histological alterations, hepatic function impairment, and dyslipidemia. Babu, P.S., and Srinivasan, K. 1997. In vivo studies in our laboratory have demonstrated that interleukin-6 (IL-6) stimulates pluripotent hematopoietic stem cell (CFU-s), granulocyte-macrophage progenitor cell (GM-CFC), and erythroid progenitor cell (CFU-e) proliferation in normal mice. 2009. Rats were pretreated for 28 d with standard drug (Livolin Forte) and oils from Z. officinale and C. longa before they were exposed to 45% ethanol (4.8 g/kg) to induce acute fatty liver. cell count, hemoglobin concentration, and hematocrit value. The bioavailability of curcumin is, due to the presence of tetrahydrocurcumin antioxidant ac-, tion (Okada et al. El-Nimr and Abdel-, Rahim (1998) have attributed the alterations in trace ele-, ment level induced by irradiation to the long term distur-, cellular activities. and chloroform fractions obtained from it were tested on eight pathogenic bacteria. (L.) in male albino rat. Herbal Drugs: Friend or Foe? 500 mg/kg represent the dose of C. xanthorrhiza. Further hepatic tissues were also subjected to histopathological studies. There was no evidence of extra-hepatic biliary obstruction, although one patient had chronic pancreatitis. As a single agent, only TPO could maintain the LTRC. Contact us at [email protected] for any enquiries. Pharmacol. Irradiation increases superoxide dismutase in rat intestinal, Syng-Ai, C., Kumari, A.L., and Khar, A. *Corresponding author. A 78-year-old woman developed asthenia and weakness. In the βOHB, D-galactose, or γ-irradiation groups, liver MDA levels and SOD activity were significantly increased. More than 80% inhibition of TNF production required four consecutive rIL-6 injections. rheumatism, cancer, hypertension and hear, nized in the West. To monitor cell division, we used membrane dye PKH26. Choisissez un traitement efficace sans effet secondaire : Nutrivitis, pour restaurer et protéger votre foie. Turmeric (Curcuma longa L.) is a widely used spice that exhibits potent anti-inflammatory response and appears to decrease indirect markers of muscle damage. 1986), and it is not toxic at higher levels of intake (Ravindra-, nath and Chandrasekhara 1982). Les transaminases, le profil lipidique, l, interleukine-6 (IL-6), le nécrose des tumeurs, extrait aqueux montrait une activité radioprotectrice sur les hépatocytes exposés à des, affectait les transaminases et les lipides, augmentait la peroxydation lipi-, IL-6 et de TNF, et diminuait les niveaux de glutathion, de supero-, améliorait le statut antioxydant et atténuait l, augmentation de la production de cytokines. Chaudhary, D., Chandra, D., and Kale, R.K. 1999. phospholipase A2 in experimental animal. Technical Reports. vein. The human body develops, body (Davies 2000). Trouvé à l'intérieur – Page 211tives desmethoxy - curcumin ( feruloyl - p - hydroxycinnamoyl methane or curcumin II ) and bisdesmethoxy - curcumin ... transaminase ( alanine aminotransferase ) and serum glutamate pyruvate transaminase ( aspartate aminotransferase ) ... manufactures protocol (Thermo Scientific, USA). Also, the enhancement of antioxidant def, mechanisms by improved antioxidant status and reduction of, This work was supported by grant NCRRT-A0121 from, the National Centre for Radiation Research and Technology, (NCRRT), Atomic Energy Authority, Cairo, Egypt. PMID: Curcuma longa (C. longa) or turmeric is a plant with a long history of use in traditional medicine, especially for treating inflammatory conditions C. longa and its main constituent, curcumin (CUR), showed various pharmacological effects such as antioxidant and anti-microbial properties. Élévation des transaminases 1 cuillère à café par jour, à diluer dans 1 verre d'eau, à consommer à jeun ÉMONCTOIRES. Trouvé à l'intérieur – Page 10The genus Curcuma was recircumscribed to include the monotypic genus Paracautleya and renamed Paracautleya bhatii as C. ... Monomorphism of malate enzyme and glutamate oxaloacetate transaminase was found in four species of Curcuma ... In this study, iron and zinc were in-, creased, while copper levels decreased. 2007. Arsenic (As) is known for its carcinogenic and hepatorenal toxic effects causing serious health problems in human beings. Trouvé à l'intérieurBiochemical analysis showed a significant increase in the levels of alanine transaminase (ALT), ... for four weeks with a polyherbal mixture (Phyllanthus niruri, Curcuma xanthorrhiza, and Curcuma longa) together with TB multitherapy. On day 7, PKH26(low) and PKH26(high) cells were prepared by sorting and their in vivo reconstituting abilities were tested by transplantation into lethally irradiated Ly-5 congenic mice together with compromised marrow cells. Conclusion: The leaves extracts of G. latifolium and A. dentate possess hepatoprotective effect. 1980. Cytotoxicity, antioxidant and anti-inflammatory activities. This work aims to investigate the possible inhibitory action of β-hydroxybutyrate (βOHB) against hematological alterations and hepatic injury associated with oxidative stress caused by D-galactose or γ-irradiation in rats. This study (28 days) was carried out to investigate the therapeutic efficacy of different doses of Cur (Cur: 80, 160, 240 mg kg . The au-, thors declare that they do have any conflict of interest associ-. Curcuma xanthorrhiza Roxb. This is the result of several trials that were, showed few peaks. Effect of gamma-radiation, Fee, J.A. Trouvé à l'intérieur – Page 554Curcuma. Extract. (Turmeric). on. Abnormally. High. Plasma. Fibrinogen. Levels. (Values ... as measured by serum glutamate oxaloacetate and serum glutamate pyruvate transaminase, when treated with 100 mg/kg of turmeric.29 The ... 84, No. Outre son utilisation alimentaire, le curcuma (ou turmeric dont on connait les bienfaits) est utilisé depuis des siècles pour ses vertus santé : il apaise, protège et agit comme un anti-inflammatoire. Conclusion: Turmerin proved to be potent antioxidant against NV-PLA 2 induced free radical formation in plasma and organs, preventing tissue damage and neutralized lethality. Level of sig-. 4(23), pp. FINDINGS: Carbon tetrachloride significantly increased lipid peroxidation and Levels of hepatic enzymes. In the acute oral toxicity study, Curcuma xanthorrhiza ethanolic extract did not show any toxic effects in mice at 5 g/kg. Humans when exposed to harmful ionising radiations suffer from various pathophysiological disorders including cancer. Mol. The biochemical findings were matched with histopathological verifications. Trouvé à l'intérieur – Page 151... as with many other Curcuma secondary metabolites, C. xanthorrhiza compounds can be swathed in the now classic antioxidant, ... alanine transaminase (SGPT), oxaloacetate transaminase (SGOT), and g-glutamyl transpeptidase (g-GT). J. Pharmacol. Trouvé à l'intérieur... from the elevations of plasma alanine transaminase (ALT) and aspartate transaminase (AST) activities, and histological analysis of liver injuries.” “Hexane extract of Curcuma comosa was given at different time points from 1 to 72 h, ... Neither IL-6 nor FL was effective by itself, but they acted synergistically to maintain the LTRC. The biochemical liver functional tests were also analyzed and it was shown that serum biomarkers of liver dysfunction, including alanine transaminase (ALT), aspartate transaminase (AST), and alkaline phosphatase (ALP) were significantly reduced in aqueous extract of Cydonia oblonga Mill. These studies demonstrate that therapeutically administered IL-6 can effectively accelerate multilineage hematopoietic recovery following radiation-induced hematopoietic injury. Arch. Measurement of reactive species 6. radioprotective effect of the aqueous extract of, hepatocytes, we determined the cell viability at different, hepatocytes indicated that 3.2 Gy was the 50% inhibitory, 36.5 µmol/L for curcumin (data not shown). METHODS: This experimental study was performed on 50 male mature albino, Objective: To comparatively investigate the hepatoprotective effect of ethanol extracts of Gongronema latifolium and Alternanthera dentate leaves in experimental rats. the effectiveness of their antioxidant activity (Piper et al. J. Immunopathol. Antiproliferative effect of curcumin (dif. tion, which results in the accumulation of cholesterol, glycerols (TGs), and phospholipids (Stepanov 1989). Plants belonging to the genus Curcuma are gaining importance globally as one of the significant ingredients in food and traditional medicines. 2005). Trouvé à l'intérieur – Page 411Rats fed cooked diets containing 0.5% or 0.05% turmeric showed no significant differences in the incidence of ... increase of serum glutamic oxalacetic and glutamic pyruvic transaminases resulting from CCl4-induced liver damage in rats. J. Obstet. Certaines protéines permettent d'augmenter la concentration de glutathion et font baisser les gamma-gt (volailles, œufs) . stellate cell activation in-vivo and in-vitro. In each patient the liver biopsy showed severe fatty change with cholestasis, but without typical alcoholic hepatitis. Madamanchi, N.R.R., and Runge, M.S. In addition, DATS pretreatment markedly suppressed the ethanol-induced decrease of the hepatic GSH level and increased the mitochondrial GSH level. The garlic and turmeric extract also decreased triglyceride in comparable fashion with simvastatin. Contact us at [email protected] for any enquiries. These results highlight the role of βOHB as a powerful protective agent against hematological alterations and liver impairment by reducing G6PD-mediated oxidative stress and controlling the measured elements. Trace elements were determined both in the liver tissue of, concentrated nitric acid and hydrogen peroxide at 5:1 ratio, Milestone MLS-1200 Mega High Performance Microwa, Digestor Unit. At the end of the experiment, complete blood picture (CBC), liver function, and lipid profile were estimated. The present investigation has been conducted to evaluate the therapeutic potential of Curcuma longa (200 mg kg −1, po) and curcumin (80 mg kg −1, po) for their hepatoprotective efficacy against mercuric chloride (HgCl 2: 12 μmol kg −1, ip; once only) hepatotoxicity.The HgCl 2 administration altered various biochemical parameters, including transaminases, alkaline phosphatase, lactate . Histological changes were observed and the degree of protection was measured by . Also, it has hypolipidemic (Babu and Srinivasan. Our results suggest that an interaction of IL-6 with IL-1 and TNF is a prerequisite for protection from radiation lethality, and its interaction with IL-1 for induction of ACTH. Various studies showed anti-inflammatory effects of C. longa and CUR, including decreased white blood cell, neutrophil, and eosinophil numbers, and its protective effects on serum levels of inflammatory mediators such as phospholipase A2 and total protein in different inflammatory disorders. 1999) Also, this effect could be attributed to the dam-, age that occurs in biomembranes, which leads to the release, dismutase-1 and peroxiredoxin-1 antibodies. The lipid peroxidation (malondialdehyde, MDA), non-enzymatic antioxidant (glutathione, GSH) and enzymatic antioxidants (superoxide dismutase, SOD; catalase, CAT; glutathione reductase, GR; glutathione peroxidase, GSH-Px) were measured both in the liver homogenate and isolated mitochondria. The ingredients that have diuretic effects in renal failure include S. crispus [21], O. stamineus [20], S. officinarum [12], and C. domestica, ... Antimicrobial [221] ; antimetastatic [87] ; anticandidal [222] ; antimycotic [88] ; chemopreventive [223] ; estrogenic [224] ; hepatoprotective and antinociceptive. Trouvé à l'intérieur – Page 247... Poncirus trifoliatus, Curcuma zeodaria, Citrus aurantium, Saussurea lappa, Glycyrrhiza glabra, and Zingiber officinale was used. Results were significant at p < 0.01 levelHV112. Glutamate–pyruvate–transaminase inhibition. Received 28 April 2011. Furthermore, levels of lipid peroxidation, nitric oxide content, and endogenous antioxidants, in addition to concentrations of copper, iron, and calcium were measured in liver tissue. 6, No. Xanthorrhizol, the main chemical component of the C. xanthorrhiza rhizome oil, has been reported to have antioxidant, antiinflammatory, antibacterial, neuroprotective, nephroprotective, hepatoprotective and estrogenic activities (Hwang et al., 2000;Kim et al., 2005;Lim et al., 2005;Anggakusuma et al., 2009; ... Histopathology of liver was carried out by a modified method of Luna [10]. Additionally, CKS protected against ethanol-induced depletion of hepatic glutathione levels. Pretreatment with CKS prior to ethanol administration significantly prevented the increases in serum alanine aminotransferase activity, hepatic TNF-alpha level, hepatic lipid peroxidation and hepatic triglyceride level. Moreover, Drobnic et al. Using curcu-, min as a standard, hepatocytes were pretreated with, High performance liquid chromatography data analysis, The mobile phase comprised acetonitrile/water. The oral administration of the extracts showed a significant (P, Essential oils composition of nine Curcuma species from Thailand: a chemotaxonomic approach, Hepatoprotective Effects of Aqueous Extract of Watermelon (Citrullus lanatus) Seeds on Ethanol-Induced Oxidative Damage in Wister Rats, Determination of quality parameters in nata de cocolawak as hepatoprotector functional food, In vivo antioxidant activities of Curcuma longa and Curcuma xanthorrhiza: a review, Effectiveness and mechanism of physician herbs from kali putih batur banjarnegara central java against diabetic nephropathy, Nutritional value, phytochemical composition, and biological activities of edible Curcuma species: A review, The rhizome volatile oils from two Thai ornamental Curcuma species, Hepatoprotective Activity of Methanolic Extract of Barleria Montana Nees Leaves in Paracetamol Induced Rat Hepatic Injury, Antibacterial and NMR analysis of Curcuma xanthorrhiza extract and fractions, Evaluation of the Antinociceptive Activity and Acute Oral Toxicity of Standardized Ethanolic Extract of the Rhizome of Curcuma xanthorrhiza Roxb, The Smaller Halogenated Aliphatic Hydrocarbons, Epidemiology and clinical aspects of hepatocellular carcinoma, Saponins isolated from the root of Platycodon grandiflorum protect against acute ethanol-induced hepatotoxicity in mice, Diallyl trisulfide (DATS) effectively attenuated oxidative stress-mediated liver injury and hepatic mitochondrial dysfunction in acute ethanol-exposed mice, Acute Cholestasis, Hepatic Failure, and Fatty Liver in the Alcoholic, Cirrhosis in the Alcoholic and its Relation to the Volume of Alcohol Abuse, Liver hypermetabolic state after chronic ethanol consumption: Horomonal interrelations and pathogenic implications, PK-PD Integration and Modelling of Mitragynine: Determination of Clinically Effective Doses for Clinical Trial, A method for preparing an immunogen and a use thereof, Antihypertension research by using aortic ring assay.
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